BDBM50581147 CHEMBL5094242

SMILES CN(C)C(=O)c1ccc(cc1)-c1cc(Nc2ncnc(Cl)c2N)c(cc1F)N1CCN(C)CC1

InChI Key InChIKey=LXONEMNSYOAQJT-UHFFFAOYSA-N

Data  7 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50581147   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DOT1L (unknown origin) assessed as effect on H3K79 methylation incubated for 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed